GS-441524 injection is a highly effective treatment for feline infectious peritonitis (FIP), a viral disease that has historically been fatal for cats. Caused by a mutation of the feline coronavirus, FIP leads to severe inflammation in vital organs, including the liver, kidneys, and brain. GS-441524, an analog of the antiviral drug remdesivir, works by inhibiting viral replication, preventing the virus from spreading and allowing the cat's immune system to mount a proper response. This injectable form is the most direct and effective method of administering the drug, ensuring rapid absorption and distribution throughout the body.
The treatment typically involves a course of daily injections over a period of weeks, depending on the severity of the disease and the cat's overall health. GS-441524 has shown high success rates in improving the condition of cats diagnosed with FIP, often leading to full recovery, particularly when the disease is caught early. Veterinary professionals closely monitor the cat’s response to treatment, adjusting the dosage as needed to optimize effectiveness.
GS-441524 injection offers hope for pet owners whose cats have been diagnosed with FIP, providing a chance at recovery where other treatments have failed. This innovative therapy has revolutionized the management of FIP, turning what was once a fatal diagnosis into a treatable condition. With its proven efficacy and safety, GS-441524 is an invaluable tool in the fight against FIP in cats.
Parameter | Value |
---|---|
Specification | 20mg/mL, 30mg/mL |
Product Shelf Life | 1 Year |
Product Form | Injections |
Product Packaging | 10 Vial Per Box |
Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
Product Usage | Cat FIPV Treatment |
Product Type | Liquid |
Test Method | HPLC UV |
Molecular Weight | C12H13N5O4 |
Product Storage | Store In A Cool, Dry Place |
Product Name | GS441 FIP Treatment |
Product Characteristics | Cat FIP, Remdesivir intermediate |
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.
【 Usage 】
Subcutaneous injection, once within 24 hours, can be injected into the neck or both sides of the back of the cat. It is recommended to switch to different areas for injection every day;
【 Dosage 】
0.4ml/kg -0.8ml/kg; Determine the dosage based on the clinical condition of the cat;
【 Preservation 】
Place in the refrigerator's freshness layer (2-4℃) and avoid direct sunlight;
【 Suggested treatment period 】
45 to 84 days, depending on the cat's re examination index and individual differences, to be determined by the doctor and owner through consultation;
【 Precautions 】
1. When injecting the injection, be careful not to hit the superficial cortex. If hit on the superficial cortex, the cat is prone to bulging, and the leakage of the medication may cause some irritation to the cat's skin; ① If any liquid medicine leaks out of the skin, it should be promptly wiped and cleaned; ② If bulging occurs, a hot towel can be applied to the bulging area for 5-10 minutes;
2. Because FIP cats generally have severe inflammation, anemia, liver, and kidney damage, during treatment, according to the reported index of cat examination, it is recommended to add corresponding auxiliary drugs, such as liver protection tablets, anti-inflammatory tablets, kidney tonics, and blood tonics;
3. Each cat has different levels of drug absorption, and generally after 3-5 days of injection treatment, the cat begins to gradually improve; If the cat still does not improve after 7-10 days of injection treatment, the owner needs to take the cat to the hospital for examination in a timely manner, and consider whether the cat is suffering from other diseases, or if the cat has cat to cat transmission and other diseases occur simultaneously;
4. This injection only treats FIP and has no therapeutic effect on other diseases. If the cat also suffers from other diseases while suffering from FIP, other diseases also need to be treated together with medication;
5. There are roughly two types of FIP:
① wet cat transmission - there is fluid accumulation in the body. If the fluid accumulation does not affect the cat's breathing, it is not recommended to remove it. After treatment, the fluid accumulation will slowly absorb and be discharged;
② Dry cat transmission - there is no fluid accumulation in the body, which is generally difficult to detect in the early stage. Viral transmission is generally stronger, so it is generally more difficult to treat compared to wet transmission. During treatment, it is recommended to use a larger amount of medication. If the virus invades the nerves and limbs, treatment may be delayed, and a small number of cat limbs may not be able to recover to their pre disease state;
6. Duration of FIP treatment:
① It is recommended that the duration of cat abdominal transmission should be at least 45 days, but this time is not fixed. It is required that under the premise of normal other indicators, the white cell ratio should be higher than 0.7 (which is the most important indicator);
② The experimental theory is continuous injection therapy for 12 weeks, which is a recommended course of treatment given by researchers through continuous exploration: it may not be suitable for all cats, but it must be suitable for most cats; If the injection stops for a short period of treatment and relapses, the dosage needs to be doubled, the cost is more expensive, and cats are also very painful. Therefore, if economic conditions allow, the closer the injection treatment is to 12 weeks, the lower the recurrence rate of cats; ③ Suggestion for stopping injection: All blood routine indicators are normal, lymphocyte percentage is normal, biochemical indicators are all normal, and globulin is within the normal range.