GS-441524 is the main plasma metabolite of the antiviral drug remdesivir, and its half-life in human patients is around 24 hours. It was found to be effective against certain feline coronavirus strains causing feline infectious peritonitis (FIP), a lethal systemic disease in cats.
FIP develops when a cat's immune system is weakened and unable to fight off the virus. Depending on the severity of the immune defect, cats with FIP can experience either wet FIP (complete immune response) or dry FIP (partial immune response).
GS441524 acts as an alternative substrate and a chain terminator of viral RNA dependent RNA polymerase; in other words, it stops the replication of the virus. In this way, GS441524 can help cats with FIP build a stronger immune defense against the virus, allowing it to heal.
| Product Attribute | Specification |
|---|---|
| Product Name | GS441 FIP Treatment |
| CAS No. | 1191237-69-0 |
| Molecular Weight | C12H13N5O4 |
| Product Packaging | 10 Vial Per Box |
| Test Method | HPLC UV |
| Shipping Method | Air (UPS, FedEx, TNT, EMS) or Sea |
| Specification | 30mg/mL, 5.5mL (Or 20mg/mL) |
| Product Form | Injections |
| Product Usage | Cat FIPV Treatment |
| Product Storage | Store In A Cool, Dry Place |
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.4mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.3mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.5mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.6mL/kg * body weight kg + 0.1 residue
Recurrence: 0.8 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.
Precautions for injection
(1) Injection method.
Subcutaneous injection, 0.3mm fine needle is recommended.
(2) Make sure your cat gets enough water.
It is very necessary for your cat to get enough water before and after the injection. If your cat is severely dehydrated, the medicine may not be fully absorbed. If you suspect that your cat may be dehydrated, ask your veterinarian for help on how to get enough fluids.
(3) Choose the right injection site.
Find a piece of loose skin. Generally speaking, the skin between the neck and back of a cat is the most loose skin.
(4) Inject medicine.
If you notice blood or medicine coming out of the injection site, use a clean cotton ball to gently press the injection site until the secretion stops.
This should only take a minute or so, but if your cat moves around too often, it may take longer.
(5) Correctly dispose of used needles.
Do not put uncovered needles in the trash can, as this may cause infection to people.
