GS-441524 injection is a highly effective treatment for feline infectious peritonitis (FIP), a severe viral disease that affects cats. This injectable medication is derived from remdesivir, a drug originally developed for treating viral infections in humans, and has been found to have promising results in curing FIP in cats. FIP is caused by a mutation of the feline coronavirus, leading to inflammation and organ failure. GS-441524 works by inhibiting viral replication, thereby preventing the virus from spreading and allowing the cat's immune system to recover.
The GS-441524 injection is administered under veterinary supervision, with precise dosage and treatment protocols tailored to the cat's weight and condition. It is known for its high success rate in treating FIP, offering hope to cats that would otherwise have a poor prognosis. Treatment duration typically lasts several weeks, with frequent injections required to ensure effective viral suppression.
This injectable form of GS-441524 is an essential option for FIP-positive cats. It is safe, well-tolerated, and provides a potential cure for a condition that was once considered fatal. Pet owners seeking a reliable solution for FIP can trust GS-441524 injections to improve their cat’s health and quality of life, making it a crucial part of modern veterinary medicine.
| Parameter | Value |
|---|---|
| Specification | 20mg/mL, 30mg/mL |
| Product Shelf Life | 1 Year |
| Product Form | Injections |
| Product Packaging | 10 Vial Per Box |
| Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
| Product Usage | Cat FIPV Treatment |
| Product Type | Liquid |
| Test Method | HPLC UV |
| Molecular Weight | C12H13N5O4 |
| Product Storage | Store In A Cool, Dry Place |
| Product Name | GS441 FIP Treatment |
| Product Characteristics | Cat FIP, Remdesivir intermediate |
Feline Infectious Peritonitis (FIP) is a fatal viral disease in cats caused by a mutation of the feline coronavirus (FCoV). While most cats infected with FCoV do not develop FIP, in some cases, the virus mutates and triggers an abnormal immune response, leading to FIP.
FCoV is common in multi-cat environments like shelters and catteries. The virus is primarily transmitted through fecal-oral contact, where cats ingest the virus from contaminated surfaces, litter boxes, or grooming each other.
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.
【 Usage 】
Subcutaneous injection, once within 24 hours, can be injected into the neck or both sides of the back of the cat. It is recommended to switch to different areas for injection every day;
【 Dosage 】
0.4ml/kg -0.8ml/kg; Determine the dosage based on the clinical condition of the cat;
【 Preservation 】
Place in the refrigerator's freshness layer (2-4℃) and avoid direct sunlight;
【 Suggested treatment period 】
45 to 84 days, depending on the cat's re examination index and individual differences, to be determined by the doctor and owner through consultation;
【 Precautions 】
1. When injecting the injection, be careful not to hit the superficial cortex. If hit on the superficial cortex, the cat is prone to bulging, and the leakage of the medication may cause some irritation to the cat's skin; ① If any liquid medicine leaks out of the skin, it should be promptly wiped and cleaned; ② If bulging occurs, a hot towel can be applied to the bulging area for 5-10 minutes;
2. Because FIP cats generally have severe inflammation, anemia, liver, and kidney damage, during treatment, according to the reported index of cat examination, it is recommended to add corresponding auxiliary drugs, such as liver protection tablets, anti-inflammatory tablets, kidney tonics, and blood tonics;
3. Each cat has different levels of drug absorption, and generally after 3-5 days of injection treatment, the cat begins to gradually improve; If the cat still does not improve after 7-10 days of injection treatment, the owner needs to take the cat to the hospital for examination in a timely manner, and consider whether the cat is suffering from other diseases, or if the cat has cat to cat transmission and other diseases occur simultaneously;
4. This injection only treats FIP and has no therapeutic effect on other diseases. If the cat also suffers from other diseases while suffering from FIP, other diseases also need to be treated together with medication;
5. There are roughly two types of FIP:
① wet cat transmission - there is fluid accumulation in the body. If the fluid accumulation does not affect the cat's breathing, it is not recommended to remove it. After treatment, the fluid accumulation will slowly absorb and be discharged;
② Dry cat transmission - there is no fluid accumulation in the body, which is generally difficult to detect in the early stage. Viral transmission is generally stronger, so it is generally more difficult to treat compared to wet transmission. During treatment, it is recommended to use a larger amount of medication. If the virus invades the nerves and limbs, treatment may be delayed, and a small number of cat limbs may not be able to recover to their pre disease state;
6. Duration of FIP treatment:
① It is recommended that the duration of cat abdominal transmission should be at least 45 days, but this time is not fixed. It is required that under the premise of normal other indicators, the white cell ratio should be higher than 0.7 (which is the most important indicator);
② The experimental theory is continuous injection therapy for 12 weeks, which is a recommended course of treatment given by researchers through continuous exploration: it may not be suitable for all cats, but it must be suitable for most cats; If the injection stops for a short period of treatment and relapses, the dosage needs to be doubled, the cost is more expensive, and cats are also very painful. Therefore, if economic conditions allow, the closer the injection treatment is to 12 weeks, the lower the recurrence rate of cats; ③ Suggestion for stopping injection: All blood routine indicators are normal, lymphocyte percentage is normal, biochemical indicators are all normal, and globulin is within the normal range.
