High Purity GS-441524 Injection 20mg/ml 30mg/ml Effective Treatment For FIP In Cats

Product Description:

GS-441524 Injection is an antiviral treatment used primarily for Feline Infectious Peritonitis (FIP), a viral disease caused by the Feline Coronavirus (FCoV). This injectable solution contains 20mg/ml or 30mg/ml of GS-441524, a powerful compound derived from remdesivir, which has been shown to effectively inhibit viral replication in infected cells. GS-441524 targets the FCoV virus by blocking the RNA polymerase enzyme, preventing further viral multiplication. This helps to reduce the viral load in cats and alleviate the symptoms of FIP, such as fever, lethargy, and fluid accumulation in the abdomen or chest.

The injection is administered subcutaneously, typically once a day for a period of 12 weeks, with the dosage based on the cat’s weight and condition. GS-441524 has demonstrated high success rates in treating both wet (effusive) and dry (non-effusive) forms of FIP, significantly improving the chances of survival and recovery in affected cats.

This treatment is considered safe for cats with minimal side effects when used under veterinary supervision. GS-441524 injection offers a reliable and effective solution for a disease that was once considered fatal, giving hope to both pet owners and veterinarians dealing with FIP. Always consult a veterinarian before starting any treatment to ensure proper administration and dosage.

Technical Parameters:

Applications:

Packing: 1 box * 10 vials
 
Recommended treatment: 12 weeks.
 
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
 
Storage
 
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
 
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.

Issues You Care About

【 Usage 】

Subcutaneous injection, once within 24 hours, can be injected into the neck or both sides of the back of the cat. It is recommended to switch to different areas for injection every day;

【 Dosage 】

0.4ml/kg -0.8ml/kg; Determine the dosage based on the clinical condition of the cat;

【 Preservation 】

Place in the refrigerator's freshness layer (2-4℃) and avoid direct sunlight;

【 Suggested treatment period 】

45 to 84 days, depending on the cat's re examination index and individual differences, to be determined by the doctor and owner through consultation;

【 Precautions 】

1. When injecting the injection, be careful not to hit the superficial cortex. If hit on the superficial cortex, the cat is prone to bulging, and the leakage of the medication may cause some irritation to the cat's skin; ① If any liquid medicine leaks out of the skin, it should be promptly wiped and cleaned; ② If bulging occurs, a hot towel can be applied to the bulging area for 5-10 minutes;

2. Because FIP cats generally have severe inflammation, anemia, liver, and kidney damage, during treatment, according to the reported index of cat examination, it is recommended to add corresponding auxiliary drugs, such as liver protection tablets, anti-inflammatory tablets, kidney tonics, and blood tonics;

3. Each cat has different levels of drug absorption, and generally after 3-5 days of injection treatment, the cat begins to gradually improve; If the cat still does not improve after 7-10 days of injection treatment, the owner needs to take the cat to the hospital for examination in a timely manner, and consider whether the cat is suffering from other diseases, or if the cat has cat to cat transmission and other diseases occur simultaneously;

4. This injection only treats FIP and has no therapeutic effect on other diseases. If the cat also suffers from other diseases while suffering from FIP, other diseases also need to be treated together with medication;

5. There are roughly two types of FIP:

① wet cat transmission - there is fluid accumulation in the body. If the fluid accumulation does not affect the cat's breathing, it is not recommended to remove it. After treatment, the fluid accumulation will slowly absorb and be discharged;

② Dry cat transmission - there is no fluid accumulation in the body, which is generally difficult to detect in the early stage. Viral transmission is generally stronger, so it is generally more difficult to treat compared to wet transmission. During treatment, it is recommended to use a larger amount of medication. If the virus invades the nerves and limbs, treatment may be delayed, and a small number of cat limbs may not be able to recover to their pre disease state;

6. Duration of FIP treatment:

① It is recommended that the duration of cat abdominal transmission should be at least 45 days, but this time is not fixed. It is required that under the premise of normal other indicators, the white cell ratio should be higher than 0.7 (which is the most important indicator);

② The experimental theory is continuous injection therapy for 12 weeks, which is a recommended course of treatment given by researchers through continuous exploration: it may not be suitable for all cats, but it must be suitable for most cats; If the injection stops for a short period of treatment and relapses, the dosage needs to be doubled, the cost is more expensive, and cats are also very painful. Therefore, if economic conditions allow, the closer the injection treatment is to 12 weeks, the lower the recurrence rate of cats; ③ Suggestion for stopping injection: All blood routine indicators are normal, lymphocyte percentage is normal, biochemical indicators are all normal, and globulin is within the normal range.