GS-441524 is a main plasma metabolite of the antiviral prodrug remdesivir, with a half-life of around 24 hours in human patients. Both remdesivir and GS-441524 have proven to be effective against feline coronavirus strains responsible for feline infectious peritonitis (FIP) - a lethal disease affecting domestic cats.
When cats have a healthy immune system, white blood cells can form antibodies to prevent the virus from replicating. However, cats that contract FIP lack the necessary immune system to do so, and the virus is able to spread throughout the cat, leading to wet or dry FIP.
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
