Oral formulations of GS-441524 have become one of the most effective and convenient options for treating feline infectious peritonitis (FIP) across various weights. These formulations are designed for easy administration, allowing owners and veterinarians to provide precise and consistent dosing based on the cat's weight (typically 3 kg, 4 kg, or 5 kg). GS-441524 works by inhibiting the replication of the FIP virus (a mutant strain of feline coronavirus) at the RNA level, thereby helping to prevent viral transmission and restore the cat's immune system.
For a 3 kg cat, the standard oral dosing regimen adjusts the appropriate GS-441524 dose per kg of body weight to ensure effective antiviral concentrations while minimizing side effects. For 4 kg and 5 kg cats, the dose is increased proportionally, maintaining the same therapeutic ratio to achieve optimal blood concentrations. This targeted dosing approach ensures consistent therapeutic efficacy across cats of varying sizes.
Compared to injectable formulations, oral GS-441524 formulations are more convenient and more compliant, especially for cats with difficult-to-administer injections or those sensitive to needles. Tablets or capsules are easy to administer at home and are reliably absorbed when taken with or after food. Most cats experience improvement within the first week of treatment, including increased appetite, increased energy, and a decrease in fever or abdominal effusion.
Treatment typically lasts 6-12 weeks, depending on the severity and type of feline infectious peritonitis (FIP) (wet, dry, or neurogenic). Regular veterinary monitoring is essential to adjust dosage as needed and ensure complete recovery.
| Appearance | Tablets |
| GS Standard | 99.5%min |
| Content | 20mg, 40mg, 50mg and 60mg |
| Application | For CAT FIP R&D Use ONLY |
| Recommended dosage | 10 mg/kg |
Diagnosing FIP is challenging and often involves a combination of clinical signs, laboratory tests, and ruling out other diseases. Common diagnostic steps include:
1. Blood tests: Elevated protein levels, high white blood cell count, and low albumin-to-globulin ratio.
2. Imaging: Ultrasound or X-rays to detect fluid accumulation.
3. Fluid analysis: Testing the fluid from the abdomen or chest for elevated protein levels and specific cell types.
4. Biopsy: Histopathological examination of affected tissues can provide a definitive diagnosis.
Recommended dosage: 10mg/KG * body weight kg
Taking time: Both taken before and after meals is ok. It is recommended to take it at a fixed time every day.
Taking method: Take it directly. If the cat does not eat it, it can also be mixed in the feed.
Storage: Store at room temperature or Store at 2~4 ° C. Avoid light. Shelf life is one year.
Recommended treatment for 12 weeks.
1. How should GS-441524 oral formulations be administered to cats of different weights (3 kg, 4 kg, and 5 kg)?
The dosage of GS-441524 oral formulations should be determined based on the cat's weight. The amount of active ingredient per kilogram ensures the correct antiviral concentration. For example, smaller cats (approximately 3 kg) require a lower daily dose, while cats weighing 4 kg and 5 kg require a correspondingly higher dose. Administration with or after meals is recommended to enhance absorption and minimize gastric irritation.
2. How long does GS-441524 treatment for FIP last?
Typically, the course of treatment is 6 to 12 weeks, depending on the severity and type of FIP (wet, dry, or neurological). Cats typically begin to show noticeable improvement within 7-10 days. However, completing the full course of treatment is crucial to prevent relapses. Regular veterinary visits are recommended to adjust the dose as needed and monitor recovery progress.
3. What are the advantages of oral GS-441524 over injections?
The oral formulation is convenient, painless, and easy to administer at home—ideal for cats who find injections stressful. When used correctly, the oral formulation is steadily absorbed and provides sustained antiviral activity. While injections may work more quickly in some severe cases, oral GS-441524 is an equally effective alternative and can improve compliance and comfort for both cats and owners.
