GS-441524 is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.
When a cat's immune system is functioning normally, white blood cells are able to fight off viruses and form antibodies to prevent it from replicating. However, cats who develop FIP are unable to do this due to an immune defect or deficiency. As a result, their white blood cells are unable to fight off the virus and allow for it to spread throughout the cat's body, leading to either wet or dry FIP.
GS441524 acts as an analog which carries out a molecular process called RNA dependent RNA polymerase. In simpler terms, this process involves GS441524 inserting itself into the chain reaction and effectively halting the virus from replicating.
| Parameters | Value |
|---|---|
| Expiry Date | 2 Years |
| Strength | 10mg, 20mg, 40mg |
| Form | Oral Tablets |
| Dosage | Once Daily |
| Storage | Room Temperature |
| Indication | Treatment Of FIP |
| Product Name | GS-441524 Tablets |
| Packaging | Bag |
| Active Ingredient | GS-441524 |
| PIF | Cat FIP Disease |
FIPNOPE GS-441524 Tablets, made in China, are an effective and potent oral tablets to effectively treat Cat FIP disease (Feline Infectious Peritonitis). The tablets have an expiry date of two years, and come in a package of bags. The dosage for the tablets is once daily, making it easy to administer for cats. GS-441524 Tablets are an effective and efficient way to treat PIF (Peritonitis in FIP).
Recommended treatment for 12 weeks.
Storage: Store at room temperature or Store at 2~4 ° C. Avoid light. Shelf life is one year.
Taking method: Take it directly. If the cat does not eat it, it can also be mixed in the feed.
Taking time: Both taken before and after meals is ok. It is recommended to take it at a fixed time every day.
Recommended dosage: 10mg/KG * body weight kg
