GS-441524 is an antiviral agent and the main active metabolite of Remdesivir. It has shown remarkable effectiveness in combating various viral infections, particularly feline infectious peritonitis (FIP), a disease caused by feline coronavirus. GS-441524 has become widely recognized in veterinary medicine, especially for its success in treating FIP.
The compound acts by inhibiting the replication of viruses. It specifically targets the viral RNA polymerase, preventing the virus from replicating its genetic material, which helps slow or stop the progression of the infection.
GS-441524 is most renowned for its role in treating feline infectious peritonitis (FIP), a condition once considered incurable. Its availability in tablet form has provided a major breakthrough, leading to remission in numerous cases.
Despite lacking formal approval as a veterinary medication, GS-441524 has been extensively used by veterinarians, particularly when other treatments have proven ineffective.
| Appearance | Tablets |
| GS Standard | 99.5%min |
| Content | 20mg, 40mg, 50mg and 60mg |
| Application | For CAT FIP R&D Use ONLY |
| Recommended dosage | 10 mg/kg |
Feline Infectious Peritonitis (FIP) is a fatal viral disease in cats caused by a mutation of the feline coronavirus (FCoV). While most cats infected with FCoV do not develop FIP, in some cases, the virus mutates and triggers an abnormal immune response, leading to FIP.
FCoV is common in multi-cat environments like shelters and catteries. The virus is primarily transmitted through fecal-oral contact, where cats ingest the virus from contaminated surfaces, litter boxes, or grooming each other.
Recommended dosage: 10mg/KG * body weight kg
Taking time: Both taken before and after meals is ok. It is recommended to take it at a fixed time every day.
Taking method: Take it directly. If the cat does not eat it, it can also be mixed in the feed.
Storage: Store at room temperature or Store at 2~4 ° C. Avoid light. Shelf life is one year.
Recommended treatment for 12 weeks.
1. Introduction to the drug
Ingredients: GS441524 is a nucleoside analog that works by inhibiting viral RNA polymerase.
Indications: Mainly used to treat feline infectious peritonitis (FIP), especially wet and dry FIP.
2. Usage
Dosage: The dosage is usually calculated based on the cat's weight. The general recommended dose is 4-10 mg/kg per day. The specific dosage should be adjusted by the veterinarian based on the cat's condition and response.
Dosage frequency: Usually once a day for at least 12 weeks. Severe cases may require longer treatment.
Dosage: The tablets should be fed directly to the cat or mixed into a small amount of food to ensure that they are completely swallowed.
3. Side effects
Common side effects: May include symptoms such as loss of appetite, nausea, vomiting, and fatigue.
Serious side effects: Rare, but may include abnormal liver and kidney function. Regular blood tests are required to monitor the cat's health.
4. Precautions
Regular check-ups: During treatment, it is recommended to take the cat to the veterinarian for regular check-ups to ensure that the treatment is effective and no serious side effects occur.
Storage Conditions: The tablets should be stored in a dry, cool place away from direct sunlight and high temperatures.
