GS-441524 is a plasma metabolite of the antiviral prodrug remdesivir that has a half-life of 24 hours in humans. It has been found to be effective in fighting off feline coronavirus strains, responsible for the lethal disease feline infectious peritonitis (FIP), in in vitro tests.
GS-441524 is a nucleoside analog antiviral drug. It is a prodrug of the active antiviral compound known as GS-443902. GS-441524 is closely related to Remdesivir, which gained attention during the COVID-19 pandemic as a potential treatment for SARS-CoV-2, the virus that causes COVID-19.
GS-441524 was initially developed by Gilead Sciences for the treatment of RNA virus infections. These compounds work by inhibiting the viral RNA-dependent RNA polymerase, which is crucial for the replication of certain RNA viruses.
One of the notable applications of GS-441524 has been in veterinary medicine, particularly in the treatment of feline infectious peritonitis (FIP). FIP is caused by a coronavirus in cats, and GS-441524 has shown promise in inhibiting the replication of this virus.
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.
