GS-441524 Tablets is formulated for oral administration and is available in three strengths of 10mg, 20mg and 40mg. It is packaged in a resealable bag to maintain the product's quality and integrity. The tablets should be stored at room temperature, and should be used before the expiry date of two years after they are manufactured. GS-441524 is an innovative pharmaceutical ingredient (PIF) with superior quality, and is the ideal choice for patients who require treatment with GS-441524 Tablets.
GS-441524 is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.
When a cat's immune system is functioning normally, white blood cells are able to fight off viruses and form antibodies to prevent it from replicating. However, cats who develop FIP are unable to do this due to an immune defect or deficiency. As a result, their white blood cells are unable to fight off the virus and allow for it to spread throughout the cat's body, leading to either wet or dry FIP.
GS441524 acts as an analog which carries out a molecular process called RNA dependent RNA polymerase. In simpler terms, this process involves GS441524 inserting itself into the chain reaction and effectively halting the virus from replicating.
| Parameter | Value |
|---|---|
| Active Ingredient | GS-441524 |
| Expiry Date | 2 Years |
| Product Name | GS-441524 Tablets |
| Storage | Room Temperature |
| Strength | 10mg, 20mg, 40mg |
| Packaging | Bag |
| Dosage | Once Daily |
| Indication | Treatment Of FIP |
| Form | Oral Tablets |
Packing: 20mg/tablet, 10 tablets/bag.
Recommended dosage: 10mg/KG * body weight kg
Taking time: Both taken before and after meals is ok. It is recommended to take it at a fixed time every day.
Taking method: Take it directly. If the cat does not eat it, it can also be mixed in the feed.
Storage: Store at room temperature or Store at 2~4 ° C. Avoid light. Shelf life is one year.
Recommended treatment for 12 weeks.
