GS-441524 is the main plasma metabolite of the antiviral preventative drug remdesivir, with a half-life of around 24 hours in human patients. Both remdesivir and GS-441524 have shown to be effective in vitro against certain strains of feline coronavirus causing feline infectious peritonitis (FIP), a disease which is lethal to domestic cats.
FIP is caused by an immune system deficiency or defect, which leads to white blood cells gradually replicating the virus rather than fighting it and building as an immunity. Typically, cats without an immune response develop wet FIP, while cats with partial immunity develop dry FIP.
GS-441524 operates as a nucleoside analog, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. An analog interjects itself into the chain reaction and stops the replication of the virus.
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.Packing and Shipping:
GS441 FIP Treatment is shipped in a standard cardboard box. The box is designed to fit the product perfectly, and comes with a foam interior to cushion the product against any bumps or drops that may occur during transit. The box should be sealed with tape to ensure that the product is securely packaged and ready to ship. All GS441 FIP Treatment orders come with an instruction sheet that includes product information, safety instructions, and an optional “How to Use” guide. The instructions are printed on a separate sheet of paper and should be included in the box with the product. The product should be labeled with the appropriate shipping information, including the customer's address, before it is sealed and shipped.
