GS-441524 is an antiviral compound and the primary active metabolite of Remdesivir. It has demonstrated significant efficacy in treating certain viral infections, most notably feline infectious peritonitis (FIP), a disease caused by feline coronavirus. GS-441524 has garnered considerable attention in veterinary medicine, particularly for its role in treating this condition.
The compound works by inhibiting viral replication. It targets the viral RNA polymerase enzyme, disrupting the virus's ability to replicate its genetic material, thereby slowing or halting the infection.
GS-441524 is especially notable for its use in treating what was once considered a fatal disease, feline infectious peritonitis (FIP). This medicine has been a breakthrough in the treatment of this disease, leading to remission in many cases.
Although not officially approved as a veterinary drug, GS-441524 has been widely adopted in the veterinary community, particularly where other treatments have failed.
| Parameter | Value |
|---|---|
| Specification | 20mg/mL, 30mg/mL |
| Product Shelf Life | 1 Year |
| Product Form | Injections |
| Product Packaging | 10 Vial Per Box |
| Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
| Product Usage | Cat FIPV Treatment |
| Product Type | Liquid |
| Test Method | HPLC UV |
| Molecular Weight | C12H13N5O4 |
| Product Storage | Store In A Cool, Dry Place |
| Product Name | GS441 FIP Treatment |
| Product Characteristics | Cat FIP, Remdesivir intermediate |
Feline Infectious Peritonitis (FIP) is a fatal viral disease in cats caused by a mutation of the feline coronavirus (FCoV). While most cats infected with FCoV do not develop FIP, in some cases, the virus mutates and triggers an abnormal immune response, leading to FIP.
FCoV is common in multi-cat environments like shelters and catteries. The virus is primarily transmitted through fecal-oral contact, where cats ingest the virus from contaminated surfaces, litter boxes, or grooming each other.
Packing: 1 box * 10 vials
Recommended treatment: 12 weeks.
Recommended dosage:*DOSAGE IS BASED ON THE WEIGHT AND SYMPTOMS*
Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue
FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue
FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue
Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue
Storage
Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.
Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.
【 Usage 】
Subcutaneous injection, once within 24 hours, can be injected into the neck or both sides of the back of the cat. It is recommended to switch to different areas for injection every day;
【 Dosage 】
0.4ml/kg -0.8ml/kg; Determine the dosage based on the clinical condition of the cat;
【 Preservation 】
Place in the refrigerator's freshness layer (2-4℃) and avoid direct sunlight;
【 Suggested treatment period 】
45 to 84 days, depending on the cat's re examination index and individual differences, to be determined by the doctor and owner through consultation
