Feline Infectious Peritonitis GS441 FIP GS-441524 PIF Tablets For Cat
|Content||20mg/tablets, 40mg/tablets, or customized|
|Application||For CAT FIP R&D Use ONLY|
|Recommended dosage||10 mg/kg|
If a cat’s immune system is healthy and mature, the white blood cells should fight off an infection or virus, and allow the cat to build up an immune response, or antibodies. Cats who develop FIP have an immune defect or deficiency that causes the white blood cells to replicate, rather than fight, the virus. Essentially, the cats immune system is spreading the virus throughout the cat’s body rather than trying to eliminate it. Cats who have no immune response develop wet FIP, while cats who have a partial immune response develop dry FIP.
The nucleoside analog GS441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. In layman’s terms, GS441524 interjects itself into the chain reaction and stops the replication of the virus.
What is FIP?
Neurogenic Feline Infectious Peritonitis (FIP) is a serious disease in cats caused by mutations in the common feline intestinal (gut) coronavirus (FeCoV). The mutation allows the otherwise trivial virus to enter intestinal macrophages (a type of immune system cell) and hitch a ride to other parts of the body, infecting the abdominal cavity, chest cavity, eyes and certain parts of the gastrointestinal tract to escape the lining of the gastrointestinal tract. Example, the brain. Normally, the feline immune system prevents clinical FIP, but in some cats infected with intestinal FeCoV, the immune system is unable to eliminate the infection and the development of clinical FIP can have devastating consequences.
Over 30% of pet cats and over 80% of breeding cats have been exposed to FeCoV (the relatively harmless intestinal form).
While the relatively harmless enteric coronavirus (FeCoV) is highly transmissible among cats, the mutated form of FIP itself does not infect other cats, and feline coronaviruses are different from the human coronaviruses that cause COVID-19.
For example: Weight 4kg cat, take 1 tablet per time per day.; Weight 8kg cat, take 2 tablets per time per day.
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