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20mg/mL GS-441524 Injection For Cat FIP Feline Infectious Peritonitis

10 vials
MOQ
US$25
Price
20mg/mL GS-441524 Injection For Cat FIP Feline Infectious Peritonitis
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Features
Specifications
Shipping Method: Air(UPS, FedEx, TNT, EMS) Or Sea
Active Ingredient: GS-441524
Form: Injections
Packaging: 10 Vial Per Box
Product Name: GS-441524 Injections
Route Of Administration: Intramuscular Or Subcutaneous
Storage: Store At 2°C To 20°C
Strength: 20mg/mL, 5.5mL
Shelf Life: 12 Months
Grade: Pharmaceutcial Grade
Function: Cat FIPV Treatment
Test Method: HPLC UV
CAS: 1191237-69-0
Molecular Weight: C12H13N5O4
Basic Infomation
Brand Name: FIPNOPE
Model Number: 20mg/mL 5.5mL
Payment & Shipping Terms
Packaging Details: 10 vials/ box
Delivery Time: 2-3 days
Payment Terms: Western Union, T/T, MoneyGram, Paypal
Supply Ability: 100000 vials per month
Product Description

 

20mg/mL GS-441524 Injection For Cat FIP Feline Infectious Peritonitis

 

Product Description

 

Appearance Transparent liquid
GS Standard 99.5%min
Size 5.5 mL
Content 20mg/mL
Application For CAT FIP R&D Use ONLY

 

GS-441524 is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.

 

If a cat’s immune system is healthy and mature, the white blood cells should fight off an infection or virus, and allow the cat to build up an immune response, or antibodies. Cats who develop FIP have an immune defect or deficiency that causes the white blood cells to replicate, rather than fight, the virus. Essentially, the cats immune system is spreading the virus throughout the cat’s body rather than trying to eliminate it. Cats who have no immune response develop wet FIP, while cats who have a partial immune response develop dry FIP.

 

The nucleoside analog GS441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. In layman’s terms, GS441524 interjects itself into the chain reaction and stops the replication of the virus.  

 

 

FIP in Cats Symptoms
 
The symptoms of FIP in cats can vary depending on the type of FIP. Wet FIP is the more common form and is characterized by fluid accumulation in the abdomen or chest. Symptoms of this form of FIP include weight loss, loss of appetite, vomiting, diarrhea, and difficulty breathing.
 
FIP Cats Treatment
 
FIP was once considered a death sentence for cats, however, hope has emerged for cats with FIP. With the availability of GS-441524 treatment, the prognosis for cats with FIP has greatly improved.
 

Packing: 1 box * 10 vials

 

Recommended treatment: 12 weeks.

 

Recommended dosage:*DOSAGE IS BASED ON THE  WEIGHT AND SYMPTOMS*

               Ascites / pleural effusion: 0.5mL/kg * body weight kg + 0.1 residue

               FIP(Wet):0.4mL/kg * body weight kg + 0.1 residue

               FIP(Dry): 0.6mL/kg * body weight kg + 0.1 residue

               Eye / nerve entry: 0.7mL/kg * body weight kg + 0.1 residue
               Recurrence: 0.9 mL/ kg * body weight kg + 0.1 residue

 

Storage

 

Store at room temperature or Store at 2~4 ° C (Better). Avoid light. Shelf life is one year.

 

Do not place in a sub-zero environment. Because this will result in the precipitation of active ingredients and the appearance of crystals, thus affecting the concentration and therapeutic effect.

 

Precautions for injection

 

(1) Injection method.

Subcutaneous injection, 0.3mm fine needle is recommended.

 

(2) Make sure your cat gets enough water.

It is very necessary for your cat to get enough water before and after the injection. If your cat is severely dehydrated, the medicine may not be fully absorbed. If you suspect that your cat may be dehydrated, ask your veterinarian for help on how to get enough fluids.

 

(3) Choose the right injection site.

Find a piece of loose skin. Generally speaking, the skin between the neck and back of a cat is the most loose skin.

 

(4) Inject medicine.

If you notice blood or medicine coming out of the injection site, use a clean cotton ball to gently press the injection site until the secretion stops.

This should only take a minute or so, but if your cat moves around too often, it may take longer.

 

(5) Correctly dispose of used needles.

Do not put uncovered needles in the trash can, as this may cause infection to people.

 

20mg/mL GS-441524 Injection For Cat FIP Feline Infectious Peritonitis 0

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